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KMID : 0614720040470100940
Journal of Korean Medical Association
2004 Volume.47 No. 10 p.940 ~ p.947
Neural Stem Cells for Neurological Disorders
³ëÀç±Ô/Roh JK
±è¸¸È£/ÁÖ°Ç/Kim MH/Chu K
Abstract
Recent progress shows that neurons suitable for transplantation can be generated from neural stem cells (NSCs) in culture, and that the adult brain produces new neurons from
its own stem cells in response to injury. In this article, we discuss how the subventricular zone of the forebrain is the most active neurogenetic area and the richest source of NSCs. This review also focuses on the nature and functional properties of
NSCs of the adult mammalian brain, and we propose our views on the strategy from bench to the clinic with particular concerns and considerations.
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